Hyaluronidase
Kelsey Feltner
Structure:
Reactions: “By catalyzing the hydrolysis of hyaluronan, a constituent of the extracellular matrix (ECM), hyaluronidase lowers the viscosity of hyaluronan, thereby increasing tissue permeability. It is, therefore, used in medicine
in conjunction with other drugs to speed their dispersion and delivery. Common
applications are opthalmic surgery, in combination with local anesthetics.” So the enzyme helps
your body absorb medicines that are injected to your skin.
Rates: “It also increases the
absorption rate of parenteral fluids given by hypodermoclysis, and is an adjunct in subcutaneous urography for improving resorption of radiopaque agents. Hyaluronidase is also used for
extravasation of hyperosmolar solutions.”
Molecular
weight: 53870.9
g/mol
REFERENCES
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